This is the recommended starting protocol for most EDs and new programs. This algorithm initiates weekly long-acting injectable …

This protocol suggests using the Brixadi® weekly dose to initiate treatment due to lower risk of opioid withdrawal. Other LAI …

• WAIT to take supplemental sublingual buprenorphine for 24 hours after injection to minimize risk of precipitating withdrawal. • …

Provider Name____________________________________ Date_________________ The Direct-to-Inject (DTI) method for opioid …

Aug 15, 2025 · These findings suggest that this protocol is a promising potential pathway for patients to start buprenorphine in the …

If the dose is tolerated without precipitated withdrawal, administer the first dose of BRIXADI Weekly 16 mg followed by BRIXADI …

Nov 7, 2024 · For both Sublocade and Brixadi, supplemental SL-BUP may be needed in the early weeks of induction for break …

Jan 1, 2026 · The protocol was adapted from one used in a large-scale emergency department trial, (D’Onofrio et al., 2021) and …

Guidance on the importance of continuing buprenorphine or methadone and starting additional medications to treat acute pain. …

Brixadi (weekly): Administer subsequent Brixadi (weekly) injections every 7 days, based on the total weekly dose that was …