Apr 30, 2025 · Multiscale simulations are essential techniques in computational chemistry, providing insights into complex phenomena across extended temporal and spatial scales.

Here we provide a brief journey through the emerging roles of PI3K to the development of preclinical and clinical PI3Ki candidates.

Abstract Photooxygenation reactions are sustainable alternatives to standard oxidation methods for the synthesis of crucial building blocks, natural products and drugs. This review is intended …

Feb 26, 2025 · This paper presents four examples of advanced web applications that we have developed during the last 20 years and demonstrates the browser’s ability to compete with …

DOAJ is an online directory that indexes and provides access to quality open access, peer-reviewed journals.

Mar 26, 2025 · In recent years, extensive research has focused on developing degraders targeting CREB-binding protein (CBP) and E1A-associated protein (EP300) - two homologous …

In this review, we discuss how chemical reactions can be transformed into machine-readable formats which can be learned by machine learning (ML) models. We present a foundation for …

Key transformations, including heterocycle formation, olefin hydrofunctionalization, and semi-pinacol rearrangements are examined in detail, highlighting the potential of photo-MHAT for …

DOI 10.2533/chimia.2001.128 复制 doi 其它 期刊：CHIMIA International Journal for Chemistry 作者：S. Porchet; Thierry Meyer 出版日期：2001-03-28 求助人 戈剌_Glaa 在 2025-07-10 …

Mar 26, 2025 · Covalent modification of lysine residues has gained significant attention due to its potential application in drug development and chemical biology. Lysine is an essential amino …