CORESTEM launched the world’s first stem cell therapy for amyotrophic lateral sclerosis in South Korea in 2015. The company is now seeking out-licensing partners as it works toward product ...

Stem cells have the ability to divide for indefinite periods in culture and give rise to multiple specialized cell types. They can develop into blood, neurons, bone, muscle, skin and other cell …

Apr 9, 2025 · Stem cell therapy for ALS has shown strong therapeutic potential, particularly through the use of mesenchymal stem cells (MSCs). MSCs can differentiate into specific cell …

Mar 1, 2023 · A promising approach may be stem cells selected or engineered to deliver optimal growth factor support at multiple sites along the neuromuscular pathway. This review covers …

Nov 1, 2023 · Stem cells may be a treatment option for ALS. This treatment is not FDA-approved, but there are ongoing clinical trials to assess how effective it is.

Jun 17, 2025 · Stem Cell Therapy in ALS: A Breakthrough in the Search for Treatment 1. Introduction: Amyotrophic Lateral Sclerosis (ALS) Amyotrophic Lateral Sclerosis (ALS), …

The accelerated pace of advancements in stem cell biology at HSCI has enabled the production of millions of motor neurons generated from mouse embryonic stem cells derived from ALS …

Mar 16, 2022 · In this review, we summarize the current progress in cellular therapy for ALS. The underlying mechanism, current clinical trials, and the pros and cons of cellular therapy using …

As such, stem cell therapy has been recently a focus of both preclinical and clinical investigations of ALS. This is because stem cells have multifaceted features that can potentially target …

Sep 12, 2022 · A gene therapy product combines astrocyte replacement with stable delivery of a neuroprotective factor; a first-in-human study demonstrated safety and will inform the design of …

SC therapy is a potentially promising new treatment for ALS and the need to better understand how to develop cell-based experimental treatments, and how to implement them in clinical …

Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell …

The purpose of this study is to determine the safety and efficacy of intrathecal treatment delivered to the cerebrospinal fluid (CSF) of mesenchymal stem cells in ALS patients every 3 months for …

Mesenchymal stem cell therapy in amyotrophic lateral sclerosis (ALS) patients: A comprehensive review of disease information and future perspectives